STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALP93924.1Sporulation sigma-E factor processing peptidase (SpoIIGA); Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. (283 aa)    
Predicted Functional Partners:
ALP92978.1
Hypothetical protein.
  
  
 0.944
ALP93925.1
RNA polymerase sporulation specific sigma factor SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.919
ALP92743.1
Stage II sporulation protein required for processing of pro-sigma-E (SpoIIR).
 
   
 0.900
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.896
ALP93556.1
Hypothetical protein; Belongs to the anti-sigma-factor antagonist family.
  
  
 0.884
ALP92593.1
Stage II sporulation protein P.
 
   
 0.862
ALP94097.1
Stage III sporulation protein AA.
  
  
 0.850
ALP93927.1
RNA polymerase sporulation specific sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.840
ALP94024.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
 
  
 0.827
ALP93931.1
Hypothetical protein; FIG011856.
 
   
 0.826
Your Current Organism:
Intestinimonas butyriciproducens
NCBI taxonomy Id: 1297617
Other names: CCUG 63529, Candidatus Clostridium anorexicus, DSM 26588, I. butyriciproducens, Intestinimonas butyriciproducens Klaring et al. 2013, Pseudoflavonifractor sp. 2-1.1, Pseudoflavonifractor sp. SRB-521-5-I, strain SRB-521-5-I
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