acnA protein (Thermosulfidibacter takaii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

gene neighborhood

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textmining

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Score

acnA

Aconitate hydratase 1. (677 aa)

Predicted Functional Partners:

gltA

0.996

icd

0.966

rplS

0.921

rpmB

0.919

rpmJ

0.915

rnc

0.913

rplE

0.913

rpsF

0.913

rpmF

0.912

rpmA

0.911

Your Current Organism:

Thermosulfidibacter takaii

NCBI taxonomy Id: 1298851
Other names: T. takaii ABI70S6, Thermosulfidibacter takaii ABI70S6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acnA	gltA	TST_0782	TST_0783	Aconitate hydratase 1.	Citrate synthase; Catalyzes both citrate generation and citrate cleavage. Part of a reversible tricarboxylic acid (TCA) cycle that can fix carbon dioxide autotrophically and may represent an ancestral mode of the conventional reductive TCA (rTCA) cycle. The direction is controlled by the available carbon source(s).	0.996
acnA	icd	TST_0782	TST_1257	Aconitate hydratase 1.	Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.	0.966
acnA	rnc	TST_0782	TST_1324	Aconitate hydratase 1.	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	0.913
acnA	rplE	TST_0782	TST_1423	Aconitate hydratase 1.	Large subunit ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.	0.913
acnA	rplS	TST_0782	TST_0390	Aconitate hydratase 1.	Large subunit ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.921
acnA	rpmA	TST_0782	TST_0538	Aconitate hydratase 1.	Large subunit ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.911
acnA	rpmB	TST_0782	TST_0690	Aconitate hydratase 1.	Large subunit ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	0.919
acnA	rpmF	TST_0782	TST_1332	Aconitate hydratase 1.	Large subunit ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.912
acnA	rpmJ	TST_0782	TST_1411	Aconitate hydratase 1.	Large subunit ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	0.915
acnA	rpsF	TST_0782	TST_1668	Aconitate hydratase 1.	Small subunit ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.913
gltA	acnA	TST_0783	TST_0782	Citrate synthase; Catalyzes both citrate generation and citrate cleavage. Part of a reversible tricarboxylic acid (TCA) cycle that can fix carbon dioxide autotrophically and may represent an ancestral mode of the conventional reductive TCA (rTCA) cycle. The direction is controlled by the available carbon source(s).	Aconitate hydratase 1.	0.996
gltA	icd	TST_0783	TST_1257	Citrate synthase; Catalyzes both citrate generation and citrate cleavage. Part of a reversible tricarboxylic acid (TCA) cycle that can fix carbon dioxide autotrophically and may represent an ancestral mode of the conventional reductive TCA (rTCA) cycle. The direction is controlled by the available carbon source(s).	Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.	0.600
icd	acnA	TST_1257	TST_0782	Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.	Aconitate hydratase 1.	0.966
icd	gltA	TST_1257	TST_0783	Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.	Citrate synthase; Catalyzes both citrate generation and citrate cleavage. Part of a reversible tricarboxylic acid (TCA) cycle that can fix carbon dioxide autotrophically and may represent an ancestral mode of the conventional reductive TCA (rTCA) cycle. The direction is controlled by the available carbon source(s).	0.600
rnc	acnA	TST_1324	TST_0782	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	Aconitate hydratase 1.	0.913
rnc	rplE	TST_1324	TST_1423	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	Large subunit ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.	0.908
rnc	rplS	TST_1324	TST_0390	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	Large subunit ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.950
rnc	rpmA	TST_1324	TST_0538	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	Large subunit ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.949
rnc	rpmB	TST_1324	TST_0690	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	Large subunit ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	0.914
rnc	rpmF	TST_1324	TST_1332	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	Large subunit ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.982