STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sthANAD(P) transhydrogenase. (475 aa)    
Predicted Functional Partners:
bkdA
2-oxoisovalerate dehydrogenase E1 component.
  
 0.998
aceF
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.972
bkdB
2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase).
 0.958
sucB
2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.951
sucA
2-oxoglutarate dehydrogenase E1 component.
 
 0.938
bkdA2
2-oxoisovalerate dehydrogenase E1 component beta subunit.
 
 0.927
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.899
gltB
Glutamate synthase (NADPH/NADH) large chain.
    
 0.883
fadH
2,4-dienoyl-CoA reductase (NADPH2).
   
 0.856
oadA
Oxaloacetate decarboxylase, alpha subunit.
    
 0.833
Your Current Organism:
Idiomarinaceae bacterium HL53
NCBI taxonomy Id: 1298881
Other names: I. bacterium HL-53, Idiomarina sp. HL-53, Idiomarinaceae bacterium HL-53
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