STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUS49145.1Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (375 aa)    
Predicted Functional Partners:
macB
Macrolide transport system ATP-binding/permease protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 0.992
CUS49144.1
Multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  0.970
CUS48194.1
Multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.882
CUS48304.1
Hydrophobe/amphiphile efflux-1 (HAE1) family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.854
CUS48844.1
Hydrophobic/amphiphilic exporter-1, HAE1 family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.818
tolC
Outer membrane protein.
 
 0.801
CUS48843.1
Hydrophobic/amphiphilic exporter-1, HAE1 family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.789
cusA
AcrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  0.744
CUS48684.1
Multidrug efflux pump subunit AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.702
CUS47338.1
Multidrug efflux pump subunit AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.666
Your Current Organism:
Idiomarinaceae bacterium HL53
NCBI taxonomy Id: 1298881
Other names: I. bacterium HL-53, Idiomarina sp. HL-53, Idiomarinaceae bacterium HL-53
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