STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J056_001232Dihydrofolate reductase. (251 aa)    
Predicted Functional Partners:
J056_001057
Thymidylate synthase.
  
 
 0.988
J056_001099
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.910
J056_002199
Thymidylate kinase.
    
 0.870
J056_004185
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
    
 0.860
J056_004344
Septin ring organizing protein mid2.
    
 0.847
J056_001491
Folylpolyglutamate synthase.
     
 0.827
J056_004156
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
     
 0.827
J056_000145
Lipoyl-binding domain-containing protein.
    
 0.799
J056_001378
DASH complex subunit dad4.
  
 
 0.754
J056_000262
GCV_T domain-containing protein.
   
 
 0.733
Your Current Organism:
Wallemia ichthyophaga
NCBI taxonomy Id: 1299270
Other names: W. ichthyophaga EXF-994, Wallemia ichthyophaga EXF-994
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