STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J056_0013243-isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (374 aa)    
Predicted Functional Partners:
J056_004763
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.996
J056_000137
Acetolactate synthase.
  
 0.970
J056_001986
ACT domain-containing protein.
  
 
 0.968
J056_000578
Threonine dehydratase.
  
 
 0.917
J056_004489
Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
 
 0.818
J056_000027
2-isopropylmalate synthase.
  
 0.790
J056_004389
Tryptophan synthase.
  
  
 0.750
J056_002926
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
  
  
 0.724
J056_003187
N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family.
  
  
 0.709
J056_000977
Histidine biosynthesis trifunctional protein.
  
  
 0.689
Your Current Organism:
Wallemia ichthyophaga
NCBI taxonomy Id: 1299270
Other names: W. ichthyophaga EXF-994, Wallemia ichthyophaga EXF-994
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