STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J056_004046D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (480 aa)    
Predicted Functional Partners:
J056_003981
Phosphoserine aminotransferase.
 
 0.999
J056_002402
Uncharacterized protein.
     
 0.932
J056_003633
Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
  
 0.912
J056_002519
Putative phosphoglycerate mutase.
   
 0.910
J056_001099
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.899
J056_001263
Glyceraldehyde-3-phosphate dehydrogenase.
    
 0.848
J056_000977
Histidine biosynthesis trifunctional protein.
  
  
 0.821
J056_004270
Uncharacterized protein.
  
 0.805
J056_004185
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.779
J056_001378
DASH complex subunit dad4.
  
 0.757
Your Current Organism:
Wallemia ichthyophaga
NCBI taxonomy Id: 1299270
Other names: W. ichthyophaga EXF-994, Wallemia ichthyophaga EXF-994
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.