STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J056_004147Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)    
Predicted Functional Partners:
J056_000922
Cytokinesis protein sepA.
    
 0.917
J056_002741
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.873
J056_002243
Uncharacterized protein.
    
 0.848
J056_000646
Actin-2; Belongs to the actin family.
   
 0.843
J056_000692
Actin.
   
 0.843
J056_001118
Actin-related protein 3; Belongs to the actin family.
   
 0.826
J056_003236
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.811
J056_001925
Cofilin; Belongs to the actin-binding proteins ADF family.
   
 0.785
J056_003109
Actin-related protein 4; Belongs to the actin family.
   
 0.784
J056_003416
Actin-related protein 10; Belongs to the actin family.
   
 0.721
Your Current Organism:
Wallemia ichthyophaga
NCBI taxonomy Id: 1299270
Other names: W. ichthyophaga EXF-994, Wallemia ichthyophaga EXF-994
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