STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J056_000011Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (777 aa)    
Predicted Functional Partners:
J056_002016
Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.967
J056_004489
Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
   
 
 
0.944
J056_002627
Citrate synthase; Belongs to the citrate synthase family.
  
 0.940
J056_000128
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.920
J056_004176
Isocitrate lyase.
  
 0.806
J056_003128
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
 
 0.754
J056_000977
Histidine biosynthesis trifunctional protein.
  
  
 0.747
J056_001081
Malate synthase; Belongs to the malate synthase family.
   
 0.730
J056_004217
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.701
J056_002743
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.686
Your Current Organism:
Wallemia ichthyophaga
NCBI taxonomy Id: 1299270
Other names: W. ichthyophaga EXF-994, Wallemia ichthyophaga EXF-994
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.