STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I601_3587Hypothetical protein. (120 aa)    
Predicted Functional Partners:
I601_3588
Hypothetical protein.
       0.854
I601_3583
Hypothetical protein.
     0.829
I601_3586
Hypothetical protein.
       0.819
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
     
 0.773
trkA_2
Trk system potassium uptake protein TrkA.
 
     0.729
trkA_1
Trk system potassium uptake protein TrkA.
 
     0.708
htpX-2
Hypothetical protein; Protease HtpX homolog; Belongs to the peptidase M48B family.
   
    0.642
I601_2678
Polyketide cyclase / dehydrase and lipid transport.
  
     0.591
dnaG_2
DNA primase.
  
  
 0.541
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.530
Your Current Organism:
Nocardioides dokdonensis
NCBI taxonomy Id: 1300347
Other names: N. dokdonensis FR1436, Nocardioides dokdonensis FR1436
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