STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gasu_27830NAD-dependent deacetylase sirtuin 4. (371 aa)    
Predicted Functional Partners:
Gasu_20650
Mono-ADP-ribosyltransferase sirtuin 6.
  
  
 0.975
Gasu_23330
Nicotinamide-nucleotide adenylyltransferase.
   
 0.930
Gasu_23340
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.924
Gasu_17780
NAD+ diphosphatase.
    
 0.923
Gasu_03550
NAD+ kinase.
  
 
 0.916
Gasu_08370
NAD+ kinase.
  
 
 0.916
Gasu_36460
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.866
Gasu_48010
NAD-dependent histone deacetylase SIR2.
  
 
 
0.663
Gasu_53280
NAD-dependent histone deacetylase SIR2.
  
  
0.590
Gasu_36550
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.589
Your Current Organism:
Galdieria sulphuraria
NCBI taxonomy Id: 130081
Other names: G. sulphuraria, SAG 17.91
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.