Gasu_60110 protein (Galdieria sulphuraria) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

Gasu_60110

Thylakoid protein. (316 aa)

Predicted Functional Partners:

psbO

0.844

Gasu_19100

0.567

Gasu_42850

0.527

Gasu_44880

0.527

Gasu_29350

0.524

Gasu_35550

0.513

Gasu_58500

0.505

Gasu_18980

0.504

Gasu_27770

0.502

Gasu_22820

0.493

Your Current Organism:

Galdieria sulphuraria

NCBI taxonomy Id: 130081
Other names: G. sulphuraria, SAG 17.91

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gasu_18980	Gasu_19100	M2X3C2	M2XL74	Uncharacterized protein.	Thylakoid lumen 15.0 kDa protein.	0.461
Gasu_18980	Gasu_22820	M2X3C2	M2X206	Uncharacterized protein.	Uncharacterized protein.	0.508
Gasu_18980	Gasu_27770	M2X3C2	M2X0B6	Uncharacterized protein.	Uncharacterized protein.	0.508
Gasu_18980	Gasu_29350	M2X3C2	M2Y1M3	Uncharacterized protein.	Uncharacterized protein.	0.567
Gasu_18980	Gasu_35550	M2X3C2	M2XG22	Uncharacterized protein.	Photosystem II Psb27 protein.	0.530
Gasu_18980	Gasu_42850	M2X3C2	M2VYB7	Uncharacterized protein.	Peptidylprolyl isomerase.	0.565
Gasu_18980	Gasu_44880	M2X3C2	M2WVH5	Uncharacterized protein.	Hydrolase.	0.544
Gasu_18980	Gasu_58500	M2X3C2	M2VTJ6	Uncharacterized protein.	Cyclase/dehydrase.	0.520
Gasu_18980	Gasu_60110	M2X3C2	M2WRB2	Uncharacterized protein.	Thylakoid protein.	0.504
Gasu_18980	psbO	M2X3C2	D4NY61	Uncharacterized protein.	Chloroplast photosystem II 33 kDa.	0.506
Gasu_19100	Gasu_18980	M2XL74	M2X3C2	Thylakoid lumen 15.0 kDa protein.	Uncharacterized protein.	0.461
Gasu_19100	Gasu_29350	M2XL74	M2Y1M3	Thylakoid lumen 15.0 kDa protein.	Uncharacterized protein.	0.524
Gasu_19100	Gasu_35550	M2XL74	M2XG22	Thylakoid lumen 15.0 kDa protein.	Photosystem II Psb27 protein.	0.540
Gasu_19100	Gasu_42850	M2XL74	M2VYB7	Thylakoid lumen 15.0 kDa protein.	Peptidylprolyl isomerase.	0.515
Gasu_19100	Gasu_44880	M2XL74	M2WVH5	Thylakoid lumen 15.0 kDa protein.	Hydrolase.	0.530
Gasu_19100	Gasu_58500	M2XL74	M2VTJ6	Thylakoid lumen 15.0 kDa protein.	Cyclase/dehydrase.	0.499
Gasu_19100	Gasu_60110	M2XL74	M2WRB2	Thylakoid lumen 15.0 kDa protein.	Thylakoid protein.	0.567
Gasu_19100	psbO	M2XL74	D4NY61	Thylakoid lumen 15.0 kDa protein.	Chloroplast photosystem II 33 kDa.	0.555
Gasu_22820	Gasu_18980	M2X206	M2X3C2	Uncharacterized protein.	Uncharacterized protein.	0.508
Gasu_22820	Gasu_27770	M2X206	M2X0B6	Uncharacterized protein.	Uncharacterized protein.	0.486

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.919

expected number of edges:

10

PPI enrichment p-value:

5.16e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006696

Ergosterol biosynthetic process

8 of 23

2.06

4.77

4.99e-12

GO:0008299

Isoprenoid biosynthetic process

6 of 14

2.15

4.17

9.02e-10

GO:0019287

Isopentenyl diphosphate biosynthetic process, mevalonate pathway

4 of 4

2.52

3.35

4.07e-07

GO:0006721

Terpenoid metabolic process

4 of 7

2.28

2.94

1.63e-06

GO:0045338

Farnesyl diphosphate metabolic process

3 of 6

2.22

2.0

0.00014

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4427

Ergosterol metabolic process

7 of 17

2.13

4.61

4.79e-11

CL:4451

Isopentenyl diphosphate biosynthetic process, mevalonate pathway

4 of 5

2.42

3.2

6.74e-07

CL:4429

Steroid biosynthesis

3 of 11

1.95

1.57

0.00075

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00900

Terpenoid backbone biosynthesis

5 of 22

1.88

2.68

8.45e-07

map00100

Steroid biosynthesis

3 of 14

1.85

1.57

0.00057

map01110

Biosynthesis of secondary metabolites

8 of 204

1.11

1.33

1.02e-06

map01100

Metabolic pathways

8 of 639

0.62

0.47

0.0029

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-191273

Cholesterol biosynthesis

6 of 18

2.04

3.55

1.45e-08

MAP-8957322

Metabolism of steroids

6 of 37

1.73

2.59

3.22e-07

MAP-556833

Metabolism of lipids

7 of 130

1.25

1.48

6.84e-06

MAP-1430728

Metabolism

7 of 484

0.68

0.42

0.0303

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0753

Steroid metabolism

3 of 6

2.22

1.82

0.00033

KW-0752

Steroid biosynthesis

3 of 6

2.22

1.82

0.00033

KW-0756

Sterol biosynthesis

2 of 5

2.12

1.15

0.0068

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00288

GHMP kinases N terminal domain

3 of 3

2.52

2.04

0.00016

PF08544

GHMP kinases C terminal

2 of 2

2.52

1.1

0.0097

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR006204

GHMP kinase N-terminal domain

3 of 3

2.52

1.75

0.00059

IPR014721

Ribosomal protein S5 domain 2-type fold, subgroup

3 of 17

1.77

0.91

0.0163

IPR036554

GHMP kinase, C-terminal domain superfamily

2 of 2

2.52

0.89

0.0238

IPR013750

GHMP kinase, C-terminal domain

2 of 2

2.52

0.89

0.0238

IPR020568

Ribosomal protein S5 domain 2-type fold

3 of 24

1.62

0.8

0.0238

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