Gasu_22820 protein (Galdieria sulphuraria) - STRING interaction network

Nodes:

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

Gasu_22820

Uncharacterized protein. (262 aa)

Predicted Functional Partners:

Gasu_30300

0.903

Gasu_54410

0.903

Gasu_27820

0.903

Gasu_27920

0.902

Gasu_16900

0.902

Gasu_38030

0.893

Gasu_21750

0.886

Gasu_20880

0.885

Gasu_11110

0.878

Gasu_60610

0.875

Your Current Organism:

Galdieria sulphuraria

NCBI taxonomy Id: 130081
Other names: G. sulphuraria, SAG 17.91

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gasu_11110	Gasu_16900	M2X5G7	M2XL93	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.999
Gasu_11110	Gasu_20880	M2X5G7	M2Y471	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.999
Gasu_11110	Gasu_21750	M2X5G7	M2XK43	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.999
Gasu_11110	Gasu_22820	M2X5G7	M2X206	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.878
Gasu_11110	Gasu_27820	M2X5G7	M2X0C1	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.999
Gasu_11110	Gasu_27920	M2X5G7	M2X0D5	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.999
Gasu_11110	Gasu_30300	M2X5G7	M2W1N9	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit beta; Belongs to the peptidase T1B family.	0.999
Gasu_11110	Gasu_38030	M2X5G7	M2XYW6	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	20S proteasome subunit beta 6.	0.999
Gasu_11110	Gasu_54410	M2X5G7	M2WSX6	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.999
Gasu_11110	Gasu_60610	M2X5G7	M2WR55	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.999
Gasu_16900	Gasu_11110	M2XL93	M2X5G7	Proteasome subunit alpha type.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.999
Gasu_16900	Gasu_20880	M2XL93	M2Y471	Proteasome subunit alpha type.	Proteasome subunit alpha type.	0.999
Gasu_16900	Gasu_21750	M2XL93	M2XK43	Proteasome subunit alpha type.	Proteasome subunit alpha type.	0.999
Gasu_16900	Gasu_22820	M2XL93	M2X206	Proteasome subunit alpha type.	Uncharacterized protein.	0.902
Gasu_16900	Gasu_27820	M2XL93	M2X0C1	Proteasome subunit alpha type.	Proteasome subunit alpha type.	0.999
Gasu_16900	Gasu_27920	M2XL93	M2X0D5	Proteasome subunit alpha type.	Proteasome subunit alpha type.	0.999
Gasu_16900	Gasu_30300	M2XL93	M2W1N9	Proteasome subunit alpha type.	Proteasome subunit beta; Belongs to the peptidase T1B family.	0.999
Gasu_16900	Gasu_38030	M2XL93	M2XYW6	Proteasome subunit alpha type.	20S proteasome subunit beta 6.	0.999
Gasu_16900	Gasu_54410	M2XL93	M2WSX6	Proteasome subunit alpha type.	Proteasome subunit alpha type.	0.999
Gasu_16900	Gasu_60610	M2XL93	M2WR55	Proteasome subunit alpha type.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.999

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Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

25

PPI enrichment p-value:

2.6e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006418

tRNA aminoacylation for protein translation

10 of 24

1.76

4.23

5.88e-14

GO:0006520

Cellular amino acid metabolic process

11 of 137

1.05

1.39

6.30e-10

GO:0044271

Cellular nitrogen compound biosynthetic process

11 of 257

0.78

0.8

1.71e-07

GO:0006139

Nucleobase-containing compound metabolic process

11 of 277

0.74

0.75

3.14e-07

GO:1901566

Organonitrogen compound biosynthetic process

11 of 310

0.69

0.67

9.69e-07

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004812

aminoacyl-tRNA ligase activity

10 of 24

1.76

4.29

2.88e-14

GO:0016874

Ligase activity

11 of 72

1.33

2.36

7.81e-13

GO:0002161

aminoacyl-tRNA editing activity

3 of 6

1.84

1.63

0.00042

GO:0005524

ATP binding

11 of 175

0.94

1.13

4.13e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 592

0.41

0.34

0.0027

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:342

tRNA aminoacylation

9 of 16

1.89

4.6

2.65e-13

CL:362

Aminoacyl-tRNA synthetase, class I, conserved site

5 of 5

2.14

3.31

1.28e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pto00970

Aminoacyl-tRNA biosynthesis

10 of 24

1.76

4.4

6.27e-15

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0030

Aminoacyl-tRNA synthetase

10 of 24

1.76

4.37

9.60e-15

KW-0436

Ligase

11 of 62

1.39

2.67

8.61e-14

KW-0648

Protein biosynthesis

8 of 35

1.5

2.59

1.33e-09

KW-0067

ATP-binding

9 of 119

1.02

1.21

2.35e-07

KW-0963

Cytoplasm

6 of 94

0.95

0.83

0.00053

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF08264

Anticodon-binding domain of tRNA ligase

3 of 3

2.14

1.53

0.0012

PF09334

tRNA synthetases class I (M)

3 of 4

2.02

1.49

0.0012

PF03129

Anticodon binding domain

2 of 3

1.97

0.78

0.0334

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR009080

Aminoacyl-tRNA synthetase, class Ia, anticodon-binding

5 of 6

2.07

2.89

8.86e-07

IPR001412

Aminoacyl-tRNA synthetase, class I, conserved site

5 of 6

2.07

2.89

8.86e-07

IPR014729

Rossmann-like alpha/beta/alpha sandwich fold

7 of 29

1.53

2.2

3.86e-07

IPR013155

Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding

3 of 3

2.14

1.61

0.00082

IPR009008

Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain

3 of 3

2.14

1.61

0.00082

(more ...)

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