STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gasu_35680DNA ligase. (671 aa)    
Predicted Functional Partners:
Gasu_35620
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.999
Gasu_12600
ATP-dependent DNA helicase 2 subunit 2 isoform 1.
   
 0.999
Gasu_28150
ATP-dependent DNA helicase 2 subunit 1 isoform 1.
   
 0.999
Gasu_38560
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
   
 0.985
Gasu_04410
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
   
 0.985
Gasu_10060
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.980
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.977
Gasu_10720
FHA domain-containing protein.
    
 0.976
Gasu_43040
DNA repair protein RAD5.
  
 0.973
Gasu_03510
Cyclin-dependent protein kinase, putative.
   
 0.959
Your Current Organism:
Galdieria sulphuraria
NCBI taxonomy Id: 130081
Other names: G. sulphuraria, SAG 17.91
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