STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gasu_16190Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (762 aa)    
Predicted Functional Partners:
Gasu_18520
POT1-like telomere end-binding protein.
    
 0.930
Gasu_10460
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
    
 0.902
Gasu_48100
H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
     
 0.896
Gasu_12600
ATP-dependent DNA helicase 2 subunit 2 isoform 1.
   
 
 0.840
Gasu_60930
Replication protein A subunit.
    
 
 0.835
Gasu_28150
ATP-dependent DNA helicase 2 subunit 1 isoform 1.
    
 
 0.832
Gasu_30000
H/ACA ribonucleoprotein complex subunit 4.
    
 0.774
Gasu_32910
tRNA pseudouridine synthase B isoform 1.
    
 0.774
Gasu_43040
DNA repair protein RAD5.
  
 
 
 0.743
Gasu_15480
Exodeoxyribonuclease V alpha subunit.
    
 0.727
Your Current Organism:
Galdieria sulphuraria
NCBI taxonomy Id: 130081
Other names: G. sulphuraria, SAG 17.91
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.