node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gasu_03040 | Gasu_11120 | M2Y9I2 | M2W7E1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.865 |
Gasu_03040 | Gasu_12770 | M2Y9I2 | M2XN35 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.929 |
Gasu_03040 | Gasu_25130 | M2Y9I2 | M2X193 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxybutyryl-CoA dehydrogenase. | 0.909 |
Gasu_03040 | Gasu_26380 | M2Y9I2 | M2Y254 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.997 |
Gasu_03040 | Gasu_30550 | M2Y9I2 | M2Y114 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Squalene monooxygenase. | 0.946 |
Gasu_03040 | Gasu_35770 | M2Y9I2 | M2XG41 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.999 |
Gasu_03040 | Gasu_49040 | M2Y9I2 | M2XCF5 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Isopentenyl-diphosphate delta-isomerase. | 0.875 |
Gasu_03040 | Gasu_52740 | M2Y9I2 | M2XB90 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Peroxisomal fatty acid beta-oxidation multifunctional protein. | 0.874 |
Gasu_03040 | Gasu_53620 | M2Y9I2 | M2XAV2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Hydroxymethylglutaryl-CoA lyase. | 0.952 |
Gasu_03040 | Gasu_55920 | M2Y9I2 | M2WSG7 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.997 |
Gasu_11120 | Gasu_03040 | M2W7E1 | M2Y9I2 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.865 |
Gasu_11120 | Gasu_25130 | M2W7E1 | M2X193 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 3-hydroxybutyryl-CoA dehydrogenase. | 0.639 |
Gasu_11120 | Gasu_26380 | M2W7E1 | M2Y254 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.902 |
Gasu_11120 | Gasu_53620 | M2W7E1 | M2XAV2 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Hydroxymethylglutaryl-CoA lyase. | 0.847 |
Gasu_11120 | Gasu_55920 | M2W7E1 | M2WSG7 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.902 |
Gasu_12770 | Gasu_03040 | M2XN35 | M2Y9I2 | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.929 |
Gasu_12770 | Gasu_25130 | M2XN35 | M2X193 | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | 3-hydroxybutyryl-CoA dehydrogenase. | 0.957 |
Gasu_12770 | Gasu_26380 | M2XN35 | M2Y254 | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.830 |
Gasu_12770 | Gasu_52740 | M2XN35 | M2XB90 | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Peroxisomal fatty acid beta-oxidation multifunctional protein. | 0.501 |
Gasu_12770 | Gasu_53620 | M2XN35 | M2XAV2 | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Hydroxymethylglutaryl-CoA lyase. | 0.968 |