STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gasu_030403-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (456 aa)    
Predicted Functional Partners:
Gasu_35770
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 
 0.999
Gasu_55920
Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.997
Gasu_26380
Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.997
Gasu_53620
Hydroxymethylglutaryl-CoA lyase.
     
 0.952
Gasu_30550
Squalene monooxygenase.
   
  
 0.946
Gasu_12770
Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.929
Gasu_25130
3-hydroxybutyryl-CoA dehydrogenase.
    
 0.909
Gasu_49040
Isopentenyl-diphosphate delta-isomerase.
  
  
 0.875
Gasu_52740
Peroxisomal fatty acid beta-oxidation multifunctional protein.
  
 0.874
Gasu_11120
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
     
 0.865
Your Current Organism:
Galdieria sulphuraria
NCBI taxonomy Id: 130081
Other names: G. sulphuraria, SAG 17.91
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