KRK47851.1 protein (Lactobacillus kimchicus)

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:

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[Homology]

Score

KRK47851.1

Alpha beta fold family hydrolase-like protein. (282 aa)

Predicted Functional Partners:

KRK48756.1

0.942

KRK47852.1

0.799

KRK47850.1

0.666

KRK47169.1

0.613

KRK47170.1

0.613

KRK47466.1

0.613

KRK47467.1

0.613

KRK47853.1

0.559

KRK47849.1

0.475

Your Current Organism:

Lactobacillus kimchicus

NCBI taxonomy Id: 1302272
Other names: L. kimchicus JCM 15530, Lactobacillus kimchicus DCY51, Lactobacillus kimchicus JCM 15530, Lactobacillus sp. DCY51

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KRK47169.1	KRK47170.1	FC96_GL000629	FC96_GL000630	Glycosyltransferase.	Glycosyltransferase.	0.987
KRK47169.1	KRK47851.1	FC96_GL000629	FC96_GL002056	Glycosyltransferase.	Alpha beta fold family hydrolase-like protein.	0.613
KRK47170.1	KRK47169.1	FC96_GL000630	FC96_GL000629	Glycosyltransferase.	Glycosyltransferase.	0.987
KRK47170.1	KRK47851.1	FC96_GL000630	FC96_GL002056	Glycosyltransferase.	Alpha beta fold family hydrolase-like protein.	0.613
KRK47466.1	KRK47467.1	FC96_GL002391	FC96_GL002392	Glycosyltransferase.	Glycosyltransferase.	0.834
KRK47466.1	KRK47851.1	FC96_GL002391	FC96_GL002056	Glycosyltransferase.	Alpha beta fold family hydrolase-like protein.	0.613
KRK47467.1	KRK47466.1	FC96_GL002392	FC96_GL002391	Glycosyltransferase.	Glycosyltransferase.	0.834
KRK47467.1	KRK47851.1	FC96_GL002392	FC96_GL002056	Glycosyltransferase.	Alpha beta fold family hydrolase-like protein.	0.613
KRK47849.1	KRK47850.1	FC96_GL002054	FC96_GL002055	Transcription regulator; Belongs to the LysR transcriptional regulatory family.	Hypothetical protein.	0.570
KRK47849.1	KRK47851.1	FC96_GL002054	FC96_GL002056	Transcription regulator; Belongs to the LysR transcriptional regulatory family.	Alpha beta fold family hydrolase-like protein.	0.475
KRK47850.1	KRK47849.1	FC96_GL002055	FC96_GL002054	Hypothetical protein.	Transcription regulator; Belongs to the LysR transcriptional regulatory family.	0.570
KRK47850.1	KRK47851.1	FC96_GL002055	FC96_GL002056	Hypothetical protein.	Alpha beta fold family hydrolase-like protein.	0.666
KRK47850.1	KRK47852.1	FC96_GL002055	FC96_GL002057	Hypothetical protein.	NAD-dependent epimerase dehydratase.	0.491
KRK47851.1	KRK47169.1	FC96_GL002056	FC96_GL000629	Alpha beta fold family hydrolase-like protein.	Glycosyltransferase.	0.613
KRK47851.1	KRK47170.1	FC96_GL002056	FC96_GL000630	Alpha beta fold family hydrolase-like protein.	Glycosyltransferase.	0.613
KRK47851.1	KRK47466.1	FC96_GL002056	FC96_GL002391	Alpha beta fold family hydrolase-like protein.	Glycosyltransferase.	0.613
KRK47851.1	KRK47467.1	FC96_GL002056	FC96_GL002392	Alpha beta fold family hydrolase-like protein.	Glycosyltransferase.	0.613
KRK47851.1	KRK47849.1	FC96_GL002056	FC96_GL002054	Alpha beta fold family hydrolase-like protein.	Transcription regulator; Belongs to the LysR transcriptional regulatory family.	0.475
KRK47851.1	KRK47850.1	FC96_GL002056	FC96_GL002055	Alpha beta fold family hydrolase-like protein.	Hypothetical protein.	0.666
KRK47851.1	KRK47852.1	FC96_GL002056	FC96_GL002057	Alpha beta fold family hydrolase-like protein.	NAD-dependent epimerase dehydratase.	0.799

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Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.924

expected number of edges:

14

PPI enrichment p-value:

4.8e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 188

1.3

2.17

1.56e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 85

1.65

3.94

1.42e-15

GO:0019843

rRNA binding

3 of 28

1.56

0.8

0.0228

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 96

1.59

3.65

3.29e-15

GO:0044391

Ribosomal subunit

6 of 71

1.46

1.88

3.62e-06

GO:0015934

Large ribosomal subunit

4 of 40

1.53

1.38

0.00057

GO:0005761

Mitochondrial ribosome

3 of 26

1.6

1.07

0.0053

GO:0005762

Mitochondrial large ribosomal subunit

2 of 13

1.72

0.71

0.0410

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2525

Structural constituent of ribosome

10 of 16

2.33

8.2

1.05e-19

CL:2522

Organellar ribosome, and SRP-dependent cotranslational protein targeting to membrane

11 of 34

2.04

6.77

1.05e-19

CL:2527

Mixed, incl. L28p-like, and Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like

5 of 5

2.53

4.62

1.01e-09

CL:2541

SRP-dependent cotranslational protein targeting to membrane

4 of 8

2.23

3.01

9.67e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

11 of 93

1.61

3.81

5.20e-16

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

10 of 157

1.34

2.2

1.75e-10

MAP-72706

GTP hydrolysis and joining of the 60S ribosomal subunit

6 of 62

1.52

1.95

4.37e-06

MAP-72689

Formation of a pool of free 40S subunits

6 of 65

1.5

1.92

4.37e-06

MAP-975956

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

6 of 67

1.49

1.9

4.37e-06

MAP-1799339

SRP-dependent cotranslational protein targeting to membrane

6 of 67

1.49

1.9

4.37e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044391

Ribosomal subunit

7 of 74

1.51

2.19

3.06e-07

GOCC:0022626

Cytosolic ribosome

5 of 54

1.5

1.68

4.13e-05

GOCC:0015934

Large ribosomal subunit

4 of 43

1.5

1.37

0.00050

GOCC:0015935

Small ribosomal subunit

3 of 30

1.53

1.03

0.0058

GOCC:0022625

Cytosolic large ribosomal subunit

3 of 31

1.52

1.02

0.0058

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

5 of 63

1.43

1.48

0.00012

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