STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvkMevalonate kinase. (292 aa)    
Predicted Functional Partners:
mvaD
Diphosphomevalonate decarboxylase.
 
  
 0.982
KXU16669.1
Phosphomevalonate kinase.
 
  
 0.968
KXU15780.1
Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 
 0.968
fni
Isopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.955
KXU15781.1
Hydroxymethylglutaryl-CoA synthase.
 
  
 0.789
KXU16666.1
Sensor histidine kinase VraS.
       0.613
KXU16667.1
Transporter associated with VraSR.
       0.613
liaR
Two component transcriptional regulator VraR.
       0.607
KXU16664.1
DNA alkylation repair enzyme.
  
    0.563
KXU16672.1
Choline binding protein J.
       0.507
Your Current Organism:
Streptococcus oralis
NCBI taxonomy Id: 1303
Other names: ATCC 35037, CCUG 13229, CCUG 24891, CIP 102922, DSM 20627, JCM 12997, LMG 14532, LMG:14532, NCTC 11427, S. oralis, strain LVG 1, strain PB 182, strain SK23
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.