STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thlA3-ketoacyl-CoA thiolase / Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)    
Predicted Functional Partners:
KXU16709.1
Trans-2,cis-3-Decenoyl-ACP isomerase.
 
 0.997
KXU15781.1
Hydroxymethylglutaryl-CoA synthase.
  
 
 0.962
accC
Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.942
pta
Phosphate acetyltransferase.
  
 
 0.923
KXU16287.1
Dihydrolipoamide acetyltransferase component (E2) of acetoin dehydrogenase complex.
  
 
 0.921
accD
Acetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 
 0.917
adhE
Alcohol dehydrogenase / Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.917
pflB
Pyruvate formate-lyase.
     
 0.915
accA
Acetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
  
 
 0.906
KXU15605.1
Butyryl-CoA dehydrogenase.
 
 
 0.877
Your Current Organism:
Streptococcus oralis
NCBI taxonomy Id: 1303
Other names: ATCC 35037, CCUG 13229, CCUG 24891, CIP 102922, DSM 20627, JCM 12997, LMG 14532, LMG:14532, NCTC 11427, S. oralis, strain LVG 1, strain PB 182, strain SK23
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