node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PurL | guaA | SORDD17_01412 | SORDD17_01214 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.975 |
PurL | guaB | SORDD17_01412 | SORDD17_00435 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.904 |
PurL | pheT | SORDD17_01412 | SORDD17_00101 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.966 |
PurL | purA | SORDD17_01412 | SORDD17_01430 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.953 |
PurL | purB | SORDD17_01412 | SORDD17_01400 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.986 |
PurL | purF | SORDD17_01412 | SORDD17_01411 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.994 |
PurL | purH | SORDD17_01412 | SORDD17_01407 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | IMP cyclohydrolase / Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.985 |
PurL | rpoB | SORDD17_01412 | SORDD17_00217 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.733 |
PurL | xpt | SORDD17_01412 | SORDD17_00023 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.746 |
guaA | PurL | SORDD17_01214 | SORDD17_01412 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | 0.975 |
guaA | guaB | SORDD17_01214 | SORDD17_00435 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | pheT | SORDD17_01214 | SORDD17_00101 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.904 |
guaA | purA | SORDD17_01214 | SORDD17_01430 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.891 |
guaA | purB | SORDD17_01214 | SORDD17_01400 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.873 |
guaA | purF | SORDD17_01214 | SORDD17_01411 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.811 |
guaA | purH | SORDD17_01214 | SORDD17_01407 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | IMP cyclohydrolase / Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.851 |
guaA | rpoB | SORDD17_01214 | SORDD17_00217 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.894 |
guaA | tkt | SORDD17_01214 | SORDD17_01554 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.529 |
guaA | xpt | SORDD17_01214 | SORDD17_00023 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.982 |
guaB | PurL | SORDD17_00435 | SORDD17_01412 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | 0.904 |