Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFZ50772.1Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: MoeZ/MoeB domain; Rhodanese-like domain; ThiF family. (386 aa)    
Predicted Functional Partners:
thiG
Glycine oxidase ThiO; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 0.990
AFZ51663.1
PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal.
 
 0.990
AFZ51390.1
PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase NifS.
   
 0.984
AFZ51940.1
Cysteine desulfurase family protein; PFAM: Aminotransferase class-V.
   
 0.984
AFZ50127.1
Molybdopterin converting factor, small subunit; PFAM: ThiS family.
  
 0.970
AFZ49349.1
Molybdopterin converting factor, large subunit; PFAM: MoaE protein.
 
 0.944
AFZ50771.1
Putative metal-dependent protease of the PAD1/JAB1 superfamily; PFAM: Mov34/MPN/PAD-1 family; manually curated.
 
 
 0.936
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
 0.907
AFZ50020.1
PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
  
 
 0.893
AFZ50562.1
PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase.
  
  
 0.836
Your Current Organism:
Dactylococcopsis salina
NCBI taxonomy Id: 13035
Other names: D. salina PCC 8305, Dactylococcopsis salina PCC 8305, Dactylococcopsis sp. PCC 8305, Myxobactron salinum PCC 8305
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