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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU59568.1Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; KEGG: stj:SALIVA_0253 4.0e-157 xerD; nucleoside-triphosphatase; Psort location: Cytoplasmic, score: 9.97. (324 aa)    
Predicted Functional Partners:
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
    0.979
KXU59567.1
Phosphodiesterase family protein; KEGG: ssr:SALIVB_0276 2.6e-82 ysnB; putative metallophosphoesterase ysnB K07095; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.946
KXU59564.1
ScpA/B protein; KEGG: ctc:CTC01529 5.0e-31 scpA; segregation and condensation protein A K05896; Psort location: Cytoplasmic, score: 9.97.
     
 0.818
KXU59563.1
Segregation and condensation protein B; KEGG: apb:SAR116_0418 1.9e-15 transcriptional regulator containing the HTH domain K06024; Psort location: Cytoplasmic, score: 9.97.
     
 0.814
KXU59565.1
Site-specific tyrosine recombinase XerD-like protein.
       0.800
KXU59566.1
CBS domain protein; KEGG: sis:LS215_2743 0.00043 hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.800
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
 
  
 0.697
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.693
SunL
Ribosomal RNA small subunit methyltransferase B; KEGG: stj:SALIVA_1502 9.1e-222 sunL; rNA-binding protein; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.660
KXU58486.1
KEGG: stj:SALIVA_1176 2.9e-60 ndk; nucleoside diphosphate kinase (NDK) (NDP kinase) (Nucleoside-2-P kinase); Psort location: Cytoplasmic, score: 9.97.
  
 0.659
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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