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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LysAKEGG: stf:Ssal_01925 3.1e-221 lysA; diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 9.97. (421 aa)    
Predicted Functional Partners:
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 0.900
LysC
Aspartate kinase; KEGG: stf:Ssal_01811 2.6e-233 lysC; aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family.
   
 0.841
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.667
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.614
DapB
KEGG: stf:Ssal_01774 1.1e-127 dapB; dihydrodipicolinate reductase; K00215 dihydrodipicolinate reductase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.612
KXU58617.1
Aminodeoxychorismate synthase, component I; KEGG: stj:SALIVA_1250 6.3e-262 pabB; para-aminobenzoate synthetase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.592
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.545
KXU59573.1
Hypothetical protein; KEGG: edi:EDI_024680 0.0080 GRIP domain-containing protein RUD3; Psort location: OuterMembrane, score: 9.52.
       0.538
Hom
KEGG: ssr:SALIVB_0491 7.6e-218 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.509
KXU58707.1
Flavodoxin-like protein; KEGG: blo:BL1749 4.7e-35 NAD(P)H oxidoreductase; K00358; Psort location: Cytoplasmic, score: 9.26.
    
  0.507
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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