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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadENAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (273 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.946
PpnK
NAD(+)/NADH kinase; KEGG: stj:SALIVA_1521 7.7e-138 ppnK; putative inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Psort location: Cytoplasmic, score: 8.96.
    
 0.937
PncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
  
 0.895
KXU59592.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.741
KXU57825.1
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.2e-13 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96.
     
 0.582
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.571
pepC
Aminopeptidase; KEGG: stj:SALIVA_0230 1.2e-233 pepC; aminopeptidase C (bleomycin hydrolase); Psort location: Cytoplasmic, score: 9.26; Belongs to the peptidase C1 family.
       0.564
PurL
KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97.
     
 0.553
BirA
biotin--[acetyl-CoA-carboxylase] ligase; KEGG: stj:SALIVA_0965 1.5e-159 birA; bifunctional biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase; Psort location: Cytoplasmic, score: 9.26.
  
  
 0.548
KXU59298.1
KEGG: stj:SALIVA_0403 2.3e-186 nadR; putative nicotinamide-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 8.96.
     
 0.541
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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