STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU59623.1KEGG: stf:Ssal_01980 1.4e-209 rseP; RIP metalloprotease RseP; K11749 regulator of sigma E protease; Psort location: CytoplasmicMembrane, score: 10.00. (420 aa)    
Predicted Functional Partners:
UppS
KEGG: stf:Ssal_01982 3.0e-129 uppS; di-trans,poly-cis-decaprenylcistransferase; K00806 undecaprenyl diphosphate synthase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.918
CdsA
KEGG: ssr:SALIVB_0216 5.6e-135 cdsA; phosphatidate cytidylyltransferase K00981; Psort location: CytoplasmicMembrane, score: 10.00.
 
    0.891
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
  
    0.789
KXU59626.1
Putative preprotein translocase, YajC subunit.
 
     0.584
SunL
Ribosomal RNA small subunit methyltransferase B; KEGG: stj:SALIVA_1502 9.1e-222 sunL; rNA-binding protein; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.551
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
    0.550
KXU57189.1
KEGG: ssr:SALIVB_2155 6.2e-200 htrA; serine protease do-like htrA (HtrALl); Psort location: Periplasmic, score: 9.44.
 
  
 0.544
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
 
    0.534
KXU57701.1
KEGG: pfe:PSF113_4779 1.4e-58 ftsA; protein FtsA K03590; Psort location: Cytoplasmic, score: 9.97.
  
    0.524
SipA
Signal peptidase I; KEGG: stj:SALIVA_1836 5.1e-109 sipA; signal peptidase I; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.511
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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