| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AdcC1 | NifR | HMPREF3219_0200168 | HMPREF3219_0200170 | ABC transporter, ATP-binding protein; KEGG: ssr:SALIVB_0205 7.5e-124 adcC; zinc (Zn2+) ABC uptake transporter ATP-binding protein; K09817 zinc transport system ATP-binding protein. | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.506 |
| AdcC1 | hslO | HMPREF3219_0200168 | HMPREF3219_0200171 | ABC transporter, ATP-binding protein; KEGG: ssr:SALIVB_0205 7.5e-124 adcC; zinc (Zn2+) ABC uptake transporter ATP-binding protein; K09817 zinc transport system ATP-binding protein. | Chaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.481 |
| KXU56434.1 | NifR | HMPREF3219_0201815 | HMPREF3219_0200170 | KEGG: stf:Ssal_02051 1.2e-125 truA; tRNA pseudouridine synthase A; K06173 tRNA pseudouridine38-40 synthase; Psort location: Cytoplasmic, score: 8.96. | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.493 |
| KXU56434.1 | SunL | HMPREF3219_0201815 | HMPREF3219_0201976 | KEGG: stf:Ssal_02051 1.2e-125 truA; tRNA pseudouridine synthase A; K06173 tRNA pseudouridine38-40 synthase; Psort location: Cytoplasmic, score: 8.96. | Ribosomal RNA small subunit methyltransferase B; KEGG: stj:SALIVA_1502 9.1e-222 sunL; rNA-binding protein; Psort location: Cytoplasmic, score: 9.97. | 0.470 |
| KXU56434.1 | guaB | HMPREF3219_0201815 | HMPREF3219_0201212 | KEGG: stf:Ssal_02051 1.2e-125 truA; tRNA pseudouridine synthase A; K06173 tRNA pseudouridine38-40 synthase; Psort location: Cytoplasmic, score: 8.96. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.519 |
| KXU56793.1 | NifR | HMPREF3219_0201625 | HMPREF3219_0200170 | DNA internalization competence protein ComEC/Rec2-like protein; Psort location: CytoplasmicMembrane, score: 10.00. | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.518 |
| KXU56793.1 | guaB | HMPREF3219_0201625 | HMPREF3219_0201212 | DNA internalization competence protein ComEC/Rec2-like protein; Psort location: CytoplasmicMembrane, score: 10.00. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.423 |
| KXU57796.1 | NifR | HMPREF3219_0201191 | HMPREF3219_0200170 | NOL1/NOP2/sun family protein; KEGG: stj:SALIVA_1097 1.6e-217 sunL; putative rRNA methyltransferase; Psort location: Cytoplasmic, score: 9.97. | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.488 |
| KXU57796.1 | SunL | HMPREF3219_0201191 | HMPREF3219_0201976 | NOL1/NOP2/sun family protein; KEGG: stj:SALIVA_1097 1.6e-217 sunL; putative rRNA methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Ribosomal RNA small subunit methyltransferase B; KEGG: stj:SALIVA_1502 9.1e-222 sunL; rNA-binding protein; Psort location: Cytoplasmic, score: 9.97. | 0.529 |
| KXU57796.1 | guaB | HMPREF3219_0201191 | HMPREF3219_0201212 | NOL1/NOP2/sun family protein; KEGG: stj:SALIVA_1097 1.6e-217 sunL; putative rRNA methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.483 |
| KXU59402.1 | NifR | HMPREF3219_0200172 | HMPREF3219_0200170 | Hypothetical protein. | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.564 |
| KXU59402.1 | hslO | HMPREF3219_0200172 | HMPREF3219_0200171 | Hypothetical protein. | Chaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.564 |
| NifR | AdcC1 | HMPREF3219_0200170 | HMPREF3219_0200168 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | ABC transporter, ATP-binding protein; KEGG: ssr:SALIVB_0205 7.5e-124 adcC; zinc (Zn2+) ABC uptake transporter ATP-binding protein; K09817 zinc transport system ATP-binding protein. | 0.506 |
| NifR | KXU56434.1 | HMPREF3219_0200170 | HMPREF3219_0201815 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | KEGG: stf:Ssal_02051 1.2e-125 truA; tRNA pseudouridine synthase A; K06173 tRNA pseudouridine38-40 synthase; Psort location: Cytoplasmic, score: 8.96. | 0.493 |
| NifR | KXU56793.1 | HMPREF3219_0200170 | HMPREF3219_0201625 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | DNA internalization competence protein ComEC/Rec2-like protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.518 |
| NifR | KXU57796.1 | HMPREF3219_0200170 | HMPREF3219_0201191 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | NOL1/NOP2/sun family protein; KEGG: stj:SALIVA_1097 1.6e-217 sunL; putative rRNA methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.488 |
| NifR | KXU59402.1 | HMPREF3219_0200170 | HMPREF3219_0200172 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Hypothetical protein. | 0.564 |
| NifR | SunL | HMPREF3219_0200170 | HMPREF3219_0201976 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Ribosomal RNA small subunit methyltransferase B; KEGG: stj:SALIVA_1502 9.1e-222 sunL; rNA-binding protein; Psort location: Cytoplasmic, score: 9.97. | 0.593 |
| NifR | guaB | HMPREF3219_0200170 | HMPREF3219_0201212 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.551 |
| NifR | hslO | HMPREF3219_0200170 | HMPREF3219_0200171 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Chaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.825 |