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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NifRTIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (325 aa)    
Predicted Functional Partners:
hslO
Chaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
  
  
 0.825
SunL
Ribosomal RNA small subunit methyltransferase B; KEGG: stj:SALIVA_1502 9.1e-222 sunL; rNA-binding protein; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.593
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
    0.584
KXU59402.1
Hypothetical protein.
       0.564
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.551
KXU56793.1
DNA internalization competence protein ComEC/Rec2-like protein; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.518
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
  
 
 0.516
AdcC1
ABC transporter, ATP-binding protein; KEGG: ssr:SALIVB_0205 7.5e-124 adcC; zinc (Zn2+) ABC uptake transporter ATP-binding protein; K09817 zinc transport system ATP-binding protein.
       0.506
KXU56434.1
KEGG: stf:Ssal_02051 1.2e-125 truA; tRNA pseudouridine synthase A; K06173 tRNA pseudouridine38-40 synthase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.493
KXU57796.1
NOL1/NOP2/sun family protein; KEGG: stj:SALIVA_1097 1.6e-217 sunL; putative rRNA methyltransferase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.488
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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