STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MecANegative regulator of genetic competence; Psort location: Cytoplasmic, score: 9.97. (249 aa)    
Predicted Functional Partners:
ClpC
ATPase family protein; KEGG: saa:SAUSA300_0510 1.3e-174 clpC; endopeptidase K03696; Psort location: Cytoplasmic, score: 9.97.
    
 
 0.786
ClpL
KEGG: ssr:SALIVB_1722 0. ATP-dependent Clp protease, ATP-binding subunit K04086; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
    
 
 0.779
ClpE
Putative negative regulator of genetic competence ClpC/MecB; KEGG: snc:HMPREF0837_11672 0. clpE; ATP dependent protease K03697; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
    
 
 0.779
EzrA
Septation ring formation regulator EzrA; KEGG: tva:TVAG_387410 4.5e-09 viral A-type inclusion protein; K02331 DNA polymerase phi subunit; Psort location: Cytoplasmic, score: 8.96.
  
     0.764
KXU57119.1
Competence protein CoiA-like protein; Psort location: Cytoplasmic, score: 8.96.
 
     0.742
KXU59134.1
Bacterial ABC transporter protein EcsB; Psort location: CytoplasmicMembrane, score: 10.00.
  
     0.719
KXU59416.1
Hypothetical protein.
       0.705
rpoE
DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
  
     0.690
KXU57700.1
Cell division protein FtsQ; KEGG: nfi:NFIA_008440 0.0013 DEAD/DEAH box helicase, putative; K14807 ATP-dependent RNA helicase DDX51/DBP6.
  
     0.688
KXU58300.1
Hypothetical protein; KEGG: stj:SALIVA_1926 4.9e-159 adenine-specific methyltransferase; Psort location: Cytoplasmic, score: 8.96.
  
     0.657
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.