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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU59426.1Cyclic nucleotide-binding domain protein; Psort location: Cytoplasmic, score: 8.96. (212 aa)    
Predicted Functional Partners:
KXU58500.1
Hypothetical protein; KEGG: stj:SALIVA_1154 6.7e-100 signal transduction histidine kinase LytS; Psort location: CytoplasmicMembrane, score: 10.00.
   
 0.942
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.873
KXU58443.1
Queuosine biosynthesis protein QueD; KEGG: ssr:SALIVB_0882 3.8e-74 ygcM; putative 6-pyruvoyl tetrahydrobiopterin synthase (PTPS) (PTP synthase) K01737; Psort location: Cytoplasmic, score: 9.26.
 
  
  0.826
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.805
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   0.773
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.766
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.734
KXU58290.1
Hypothetical protein; KEGG: ssr:SALIVB_2004 1.2e-102 rpoC; DNA-directed RNA polymerase subunit beta K03046; Psort location: Cytoplasmic, score: 9.97.
    
 
 0.734
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.730
KXU57257.1
Glycerol facilitator-aquaporin; KEGG: hiq:CGSHiGG_06740 3.3e-20 glpQ; glycerophosphodiester phosphodiesterase K02440; Psort location: CytoplasmicMembrane, score: 10.00.
   
 0.705
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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