def protein (Streptococcus salivarius) - STRING interaction network

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def

Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (204 aa)

Predicted Functional Partners:

rpsO

0.863

rplU

0.846

rplM

0.820

rplD

0.811

rpsP

0.811

Tig

0.810

rpsT

0.808

rplT

0.807

rpsD

0.806

rplS

0.803

Your Current Organism:

Streptococcus salivarius

NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Tig	def	HMPREF3219_0200214	HMPREF3219_0200197	Trigger factor; KEGG: sgg:SGGBAA2069_c02840 2.3e-193 tig; trigger factor K03545; Psort location: Cytoplasmic, score: 8.96.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.810
Tig	rplD	HMPREF3219_0200214	HMPREF3219_0200340	Trigger factor; KEGG: sgg:SGGBAA2069_c02840 2.3e-193 tig; trigger factor K03545; Psort location: Cytoplasmic, score: 8.96.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.946
Tig	rplM	HMPREF3219_0200214	HMPREF3219_0200577	Trigger factor; KEGG: sgg:SGGBAA2069_c02840 2.3e-193 tig; trigger factor K03545; Psort location: Cytoplasmic, score: 8.96.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.962
Tig	rplS	HMPREF3219_0200214	HMPREF3219_0202107	Trigger factor; KEGG: sgg:SGGBAA2069_c02840 2.3e-193 tig; trigger factor K03545; Psort location: Cytoplasmic, score: 8.96.	Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.912
Tig	rplT	HMPREF3219_0200214	HMPREF3219_0201879	Trigger factor; KEGG: sgg:SGGBAA2069_c02840 2.3e-193 tig; trigger factor K03545; Psort location: Cytoplasmic, score: 8.96.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.848
Tig	rplU	HMPREF3219_0200214	HMPREF3219_0200276	Trigger factor; KEGG: sgg:SGGBAA2069_c02840 2.3e-193 tig; trigger factor K03545; Psort location: Cytoplasmic, score: 8.96.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.931
Tig	rpsD	HMPREF3219_0200214	HMPREF3219_0200229	Trigger factor; KEGG: sgg:SGGBAA2069_c02840 2.3e-193 tig; trigger factor K03545; Psort location: Cytoplasmic, score: 8.96.	Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.952
Tig	rpsO	HMPREF3219_0200214	HMPREF3219_0200194	Trigger factor; KEGG: sgg:SGGBAA2069_c02840 2.3e-193 tig; trigger factor K03545; Psort location: Cytoplasmic, score: 8.96.	Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.	0.878
Tig	rpsP	HMPREF3219_0200214	HMPREF3219_0201603	Trigger factor; KEGG: sgg:SGGBAA2069_c02840 2.3e-193 tig; trigger factor K03545; Psort location: Cytoplasmic, score: 8.96.	Ribosomal protein S16; KEGG: apb:SAR116_1817 1.8e-19 30S ribosomal protein S16 K02959; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bS16 family.	0.885
Tig	rpsT	HMPREF3219_0200214	HMPREF3219_0200671	Trigger factor; KEGG: sgg:SGGBAA2069_c02840 2.3e-193 tig; trigger factor K03545; Psort location: Cytoplasmic, score: 8.96.	Ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.883
def	Tig	HMPREF3219_0200197	HMPREF3219_0200214	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Trigger factor; KEGG: sgg:SGGBAA2069_c02840 2.3e-193 tig; trigger factor K03545; Psort location: Cytoplasmic, score: 8.96.	0.810
def	rplD	HMPREF3219_0200197	HMPREF3219_0200340	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.811
def	rplM	HMPREF3219_0200197	HMPREF3219_0200577	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.820
def	rplS	HMPREF3219_0200197	HMPREF3219_0202107	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.803
def	rplT	HMPREF3219_0200197	HMPREF3219_0201879	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.807
def	rplU	HMPREF3219_0200197	HMPREF3219_0200276	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.846
def	rpsD	HMPREF3219_0200197	HMPREF3219_0200229	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.806
def	rpsO	HMPREF3219_0200197	HMPREF3219_0200194	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.	0.863
def	rpsP	HMPREF3219_0200197	HMPREF3219_0201603	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S16; KEGG: apb:SAR116_1817 1.8e-19 30S ribosomal protein S16 K02959; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bS16 family.	0.811
def	rpsT	HMPREF3219_0200197	HMPREF3219_0200671	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.808

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