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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU59433.1Putative 2',3'-cyclic-nucleotide 2'-phosphodiesterase; KEGG: ssr:SALIVB_0178 0. 5-nucleotidase/2, 3-cyclic phosphodiesterase-like protein; K01119 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Psort location: Periplasmic, score: 9.44. (846 aa)    
Predicted Functional Partners:
KXU56110.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: stj:SALIVA_1473 0. zmpB; Zinc metalloprotease zmpB; Psort location: OuterMembrane, score: 9.49.
   
 0.787
KXU59436.1
Hydrolase, NUDIX family; KEGG: ste:STER_0195 2.6e-66 ADP-ribose pyrophosphatase; K03574 7,8-dihydro-8-oxoguanine triphosphatase; Psort location: Cytoplasmic, score: 8.96.
 
     0.737
KXU58541.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 4.4e-190 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.44.
  
0.734
KXU57189.1
KEGG: ssr:SALIVB_2155 6.2e-200 htrA; serine protease do-like htrA (HtrALl); Psort location: Periplasmic, score: 9.44.
   
 
 0.613
KXU59631.1
Endonuclease/exonuclease/phosphatase family protein; KEGG: ssr:SALIVB_0209 2.3e-145 exodeoxyribonuclease III K06896; Psort location: Cytoplasmic, score: 8.96.
   
  
 0.585
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
   0.564
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 
 0.550
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 
 0.541
rpsZ
Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
 
 0.529
rplW
Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
   
 
 0.527
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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