close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prmARibosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (317 aa)    
Predicted Functional Partners:
KXU59434.1
KEGG: ssr:SALIVB_0177 5.5e-121 rsmE; ribosomal RNA small subunit methyltransferase E K09761; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.923
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.897
KXU59436.1
Hydrolase, NUDIX family; KEGG: ste:STER_0195 2.6e-66 ADP-ribose pyrophosphatase; K03574 7,8-dihydro-8-oxoguanine triphosphatase; Psort location: Cytoplasmic, score: 8.96.
       0.800
KXU59437.1
Hypothetical protein.
       0.773
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
  
 0.769
SunL
Ribosomal RNA small subunit methyltransferase B; KEGG: stj:SALIVA_1502 9.1e-222 sunL; rNA-binding protein; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.659
KXU57796.1
NOL1/NOP2/sun family protein; KEGG: stj:SALIVA_1097 1.6e-217 sunL; putative rRNA methyltransferase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.626
PurL
KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97.
  
  
 0.556
KXU59438.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.485
rsmG
16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
 
  
 0.479
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.