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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (373 aa)    
Predicted Functional Partners:
KXU59365.1
Membrane protein, MarC family; KEGG: ecx:EcHS_A3634 2.4e-17 dITP- and XTP- hydrolase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.800
mnmG
tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
 
 
 0.772
KXU57800.1
Riboflavin biosynthesis protein RibF; KEGG: stj:SALIVA_1101 2.6e-153 ribC; riboflavin kinase/FMN adenylyltransferase; Psort location: Cytoplasmic, score: 9.97.
 
    0.749
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 
 0.663
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
  
 0.618
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 
 0.590
RplI
Ribosomal protein L9; KEGG: apb:SAR116_0644 4.2e-11 50S ribosomal protein L9 K02939; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.572
SunL
Ribosomal RNA small subunit methyltransferase B; KEGG: stj:SALIVA_1502 9.1e-222 sunL; rNA-binding protein; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.560
PheT
KEGG: stf:Ssal_00892 0. pheT; phenylalanyl-tRNA synthetase subunit beta; K01890 phenylalanyl-tRNA synthetase beta chain; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.556
KXU56161.1
KEGG: stf:Ssal_00615 4.2e-185 iscS; cysteine desulfurase; K04487 cysteine desulfurase; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.546
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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