STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU59290.1RelA/SpoT domain protein; KEGG: ssr:SALIVB_0431 2.1e-103 GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96. (207 aa)    
Predicted Functional Partners:
KXU59288.1
Histidine kinase A domain protein; KEGG: ssr:SALIVB_0433 4.6e-195 dltS; sensor protein dltS; Psort location: CytoplasmicMembrane, score: 9.82.
 
   
 0.943
KXU59289.1
KEGG: rha:RHA1_ro05622 7.4e-30 response regulator (protein-glutamate methylesterase) K07669; Psort location: Cytoplasmic, score: 9.97.
   
 0.910
RelA
GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.565
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
    0.559
KXU58486.1
KEGG: stj:SALIVA_1176 2.9e-60 ndk; nucleoside diphosphate kinase (NDK) (NDP kinase) (Nucleoside-2-P kinase); Psort location: Cytoplasmic, score: 9.97.
    
  0.501
Dgk
KEGG: stw:Y1U_C0595 5.0e-63 Diacylglycerol kinase; K00901 diacylglycerol kinase; Psort location: CytoplasmicMembrane, score: 10.00.
     
  0.499
mnmG
tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
   
    0.485
KXU59291.1
Acetyltransferase, GNAT family; KEGG: ssr:SALIVB_0430 1.3e-101 pac; puromycin N-acetyltransferase; Psort location: Cytoplasmic, score: 8.96.
       0.478
KXU56156.1
Rhamnan synthesis protein F; KEGG: ssr:SALIVB_0554 5.2e-235 lipopolysaccharide biosynthesis protein; K07272 rhamnosyltransferase; Psort location: Cytoplasmic, score: 8.96.
   
    0.459
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
       0.433
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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