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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIThiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (407 aa)    
Predicted Functional Partners:
NifS2
Aminotransferase, class V; KEGG: stf:Ssal_01786 3.9e-191 iscS; cysteine desulfurase; K04487 cysteine desulfurase; Psort location: Cytoplasmic, score: 9.97.
 
 0.991
SunL
Ribosomal RNA small subunit methyltransferase B; KEGG: stj:SALIVA_1502 9.1e-222 sunL; rNA-binding protein; Psort location: Cytoplasmic, score: 9.97.
   
    0.874
KXU56161.1
KEGG: stf:Ssal_00615 4.2e-185 iscS; cysteine desulfurase; K04487 cysteine desulfurase; Psort location: Cytoplasmic, score: 9.97.
 0.729
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
  
   
 0.613
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
 
 0.590
KXU59309.1
Hypothetical protein; KEGG: sgg:SGGBAA2069_c13330 1.8e-33 yndA; putative GCN5-related N-acetyltransferase.
       0.588
KXU57796.1
NOL1/NOP2/sun family protein; KEGG: stj:SALIVA_1097 1.6e-217 sunL; putative rRNA methyltransferase; Psort location: Cytoplasmic, score: 9.97.
  
    0.567
KXU59310.1
KEGG: aur:HMPREF9243_0771 3.7e-90 gtfB; accessory Sec system glycosyltransferase GtfB.
       0.546
KXU59313.1
Hypothetical protein; KEGG: ctp:CTRG_05827 1.5e-08 hypothetical protein; K01183 chitinase.
       0.545
KXU59311.1
KEGG: suz:MS7_2653 3.7e-154 gtfA; accessory Sec system glycosylation protein GtfA; Psort location: Cytoplasmic, score: 8.96.
       0.542
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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