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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NifS2Aminotransferase, class V; KEGG: stf:Ssal_01786 3.9e-191 iscS; cysteine desulfurase; K04487 cysteine desulfurase; Psort location: Cytoplasmic, score: 9.97. (381 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.991
NifU
SUF system FeS assembly protein, NifU family; KEGG: pfe:PSF113_1013 2.4e-08 iscU; protein IscU K04488.
 
 0.973
KXU58312.1
Hypothetical protein; KEGG: fpl:Ferp_2210 4.0e-06 SirA family protein; K04085 tRNA 2-thiouridine synthesizing protein A.
   
 0.829
KXU57355.1
Transcriptional regulator; KEGG: apb:SAR116_0013 0.0025 BadM/Rrf2 family transcriptional regulator.
  
  
 0.691
acpP
Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 0.674
dltC
D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
    
 0.674
KXU57603.1
Putative acyl carrier protein; KEGG: cgr:CAGL0J04664g 1.9e-08 hypothetical protein; K03955 NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1; Psort location: Cytoplasmic, score: 8.96.
    
 0.674
KXU59313.1
Hypothetical protein; KEGG: ctp:CTRG_05827 1.5e-08 hypothetical protein; K01183 chitinase.
       0.625
sufC
FeS assembly ATPase SufC; KEGG: snc:HMPREF0837_11625 1.5e-118 ABC transporter ATP-binding protein K09013; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.534
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
 
 0.518
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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