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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU59340.1Regulatory protein RecX; KEGG: erh:ERH_0631 1.9e-11 bifunctional group 1 glycosyl transferase/recombination regulator RecX; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 8.96. (258 aa)    
Predicted Functional Partners:
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity); Belongs to the RecA family.
  
 
 0.897
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.789
KXU57605.1
DNA repair protein RecO; KEGG: lec:LGMK_02530 4.7e-31 L-asparaginase; K01424 L-asparaginase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.650
KXU59339.1
23S rRNA (uracil-5-)-methyltransferase RumA; KEGG: stj:SALIVA_0357 3.4e-215 tRNA methyltransferase, TrmA family; Psort location: Cytoplasmic, score: 9.97.
  
    0.623
KXU59341.1
Hypothetical protein; KEGG: mpu:MYPU_1770 8.2e-22 cysS; cysteinyl-tRNA synthetase (cysteine--tRNA ligase) K01883; Psort location: Cytoplasmic, score: 9.97; Belongs to the UPF0374 family.
       0.623
KXU56460.1
KEGG: stf:Ssal_01390 5.7e-158 holA; DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cytoplasmic, score: 8.96.
 
     0.586
KXU57825.1
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.2e-13 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96.
     
 0.582
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.574
KXU56793.1
DNA internalization competence protein ComEC/Rec2-like protein; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.520
RecG
KEGG: ssr:SALIVB_1850 0. recG; ATP-dependent DNA helicase recG K03655; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.512
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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