STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa)    
Predicted Functional Partners:
RuvA
KEGG: stj:SALIVA_0068 2.1e-96 ruvA; holliday junction ATP-dependent DNA helicase ruvA; Psort location: Cytoplasmic, score: 9.26.
 
 0.999
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.750
LigA
DNA ligase; KEGG: stf:Ssal_00503 0. ligA; NAD-dependent DNA ligase; K01972 DNA ligase (NAD+); Psort location: Cytoplasmic, score: 9.97.
  
   
 0.745
queA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
  
  
 0.739
RecJ
KEGG: stf:Ssal_01299 0. recJ; single-stranded-DNA-specific exonuclease RecJ; K07462 single-stranded-DNA-specific exonuclease; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.682
uvrA
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 
 0.658
nusG
Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.
   
  
 0.638
KXU59258.1
Acyltransferase; KEGG: stj:SALIVA_1991 0. oatA; O-acetyltransferase oatA; Psort location: CytoplasmicMembrane, score: 10.00.
  
    0.620
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
 
 0.613
DnaG
DNA primase; KEGG: stf:Ssal_00588 0. dnaG; DNA primase; K02316 DNA primase; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.613
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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