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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polADNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (879 aa)    
Predicted Functional Partners:
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity); Belongs to the RecA family.
 
 0.999
DnaN
KEGG: ssr:SALIVB_0002 1.2e-185 dnaN; beta subunit of DNA polymerase III; K02338 DNA polymerase III subunit beta; Psort location: Cytoplasmic, score: 9.26.
 
 0.999
KXU56112.1
KEGG: stj:SALIVA_1471 1.7e-204 sbcD; exonuclease; Psort location: Cytoplasmic, score: 9.97.
  
 0.991
KXU58436.1
KEGG: stf:Ssal_00957 0. dinG; DnaQ family exonuclease/DinG family helicase; K03722 ATP-dependent DNA helicase DinG; Psort location: Cytoplasmic, score: 9.97.
  
 0.984
KXU59584.1
KEGG: ssr:SALIVB_0259 0. Snf2 family protein; Psort location: Cytoplasmic, score: 8.96.
  
 0.971
MutS1
KEGG: btl:BALH_3397 3.7e-202 mutS; DNA mismatch repair protein MutS K03555; Psort location: Cytoplasmic, score: 9.97.
   
 0.969
MutL
KEGG: btk:BT9727_3509 5.6e-151 mutL; DNA mismatch repair protein K03572; Psort location: Cytoplasmic, score: 9.97.
   
 0.965
KXU58521.1
Type III restriction enzyme, res subunit; KEGG: hwc:Hqrw_2960 8.3e-05 rad25c; DNA repair helicase Rad25.
  
 0.962
KXU56679.1
DNA-formamidopyrimidine glycosylase; KEGG: ssr:SALIVB_1452 3.3e-130 mutM; formamidopyrimidine-DNA glycosylase K10563; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.961
KXU56113.1
KEGG: stj:SALIVA_1470 0. sbcC; exonuclease; Psort location: Cytoplasmic, score: 9.97.
  
 0.951
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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