STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU58827.1DNA polymerase III, alpha subunit; KEGG: stj:SALIVA_0086 0. polC; DNA polymerase III polC-type (PolIII); Psort location: Cytoplasmic, score: 9.97. (1464 aa)    
Predicted Functional Partners:
KXU59147.1
Hydrolase, HD family; KEGG: sgg:SGGBAA2069_c18170 1.5e-79 HD domain-containing protein; Psort location: Cytoplasmic, score: 8.96.
  
     0.716
KXU59144.1
Hypothetical protein; KEGG: efc:EFAU004_01307 8.8e-66 nucleotidyltransferase; Psort location: Cytoplasmic, score: 8.96.
  
    0.624
KXU59367.1
DHHA1 domain protein; KEGG: sax:USA300HOU_0014 1.5e-93 DHH subfamily phosphodiesterase; Psort location: CytoplasmicMembrane, score: 9.82.
  
     0.622
KXU59266.1
Hypothetical protein; Belongs to the UPF0297 family.
  
     0.607
KXU58450.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
 
     0.593
mrnC
RNase3 domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.
  
    0.571
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.536
PepS
KEGG: stj:SALIVA_0087 6.2e-216 pepS; aminopeptidase pepS; Psort location: Cytoplasmic, score: 8.96.
       0.529
KXU57825.1
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.2e-13 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.479
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.472
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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