STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (328 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; KEGG: stj:SALIVA_0892 2.2e-250 pyk; pyruvate kinase; Psort location: Cytoplasmic, score: 9.97.
  
 0.972
pflB
KEGG: ssr:SALIVB_1775 0. pfl; formate acetyltransferase K00656; Psort location: Cytoplasmic, score: 9.94.
   
 
 0.946
spxB
Pyruvate oxidase; KEGG: sgo:SGO_0292 0. spxB; pyruvate oxidase K00158; Psort location: CytoplasmicMembrane, score: 7.88; Belongs to the TPP enzyme family.
  
 0.938
AcoB2
KEGG: stf:Ssal_01137 2.6e-169 pdhB; pyruvate dehydrogenase E1 component subunit beta; K00162 pyruvate dehydrogenase E1 component subunit beta; Psort location: Cytoplasmic, score: 9.97.
  
 0.918
AcoA2
KEGG: stj:SALIVA_1066 7.9e-168 acetoin dehydrogenase complex, E1 component,alpha subunit; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.908
pgi
KEGG: stj:SALIVA_0191 2.7e-238 pgi; glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI); Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family.
  
 
 0.901
Tkt
Transketolase; KEGG: ssr:SALIVB_1600 0. tkt; transketolase (TK) K00615; Psort location: Cytoplasmic, score: 9.26.
  
 0.852
fba
Fructose-1,6-bisphosphate aldolase, class II; KEGG: stj:SALIVA_1958 4.4e-151 fba; fructose-bisphosphate aldolase; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.843
GapN
KEGG: stj:SALIVA_0805 4.3e-240 gapN; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase) (glyceraldehyde-3-phosphate dehydrogenase [NADP+]) (triosephosphate dehydrogenase); Psort location: Cytoplasmic, score: 9.97.
  
 0.841
IlvH
KEGG: ssr:SALIVB_2010 2.1e-73 ilvH; acetolactate synthase small subunit K01653; Psort location: Cytoplasmic, score: 9.97.
   
 0.839
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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