STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU58601.1Adenosine deaminase; KEGG: ssr:SALIVB_0834 2.9e-163 add; adenosine deaminase K01488; Psort location: Cytoplasmic, score: 9.97. (348 aa)    
Predicted Functional Partners:
KXU56243.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.716
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.630
KXU58600.1
KEGG: scp:HMPREF0833_10782 7.1e-128 gst; glutathione S-transferase K11209; Psort location: Cytoplasmic, score: 9.97.
       0.588
KXU58541.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 4.4e-190 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.44.
    
 0.558
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.546
deoD
KEGG: stf:Ssal_01032 4.4e-119 deoD; purine nucleoside phosphorylase; K03784 purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 9.97.
    
 0.545
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.499
tdk
Thymidine kinase; KEGG: stj:SALIVA_1264 4.6e-92 tdk; thymidine kinase; Psort location: Cytoplasmic, score: 9.97.
       0.496
KXU58599.1
DHHA1 domain protein; KEGG: sgg:SGGBAA2069_c07150 2.9e-131 DHH family phosphatase protein K06881; Psort location: Cytoplasmic, score: 8.96.
       0.472
KXU56312.1
Hypothetical protein.
  
     0.468
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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