close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU58607.1Hypothetical protein; KEGG: stz:SPYALAB49_000865 2.0e-130 phosphoenolpyruvate carboxylase; Psort location: Cytoplasmic, score: 8.96. (325 aa)    
Predicted Functional Partners:
KXU58608.1
Pneumococcal vaccine antigen A-like family protein.
 
     0.829
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.800
KXU58609.1
KEGG: sgg:SGGBAA2069_c10180 1.4e-193 ABC transporter membrane protein K06148; Psort location: CytoplasmicMembrane, score: 10.00.
       0.708
KXU58610.1
KEGG: sgg:SGGBAA2069_c10190 4.9e-207 ABC transporter ATP-binding protein/permease K06147; Psort location: CytoplasmicMembrane, score: 10.00.
       0.708
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
       0.589
KXU58604.1
protein-(glutamine-N5) methyltransferase; KEGG: ssr:SALIVB_0837 5.9e-124 hemK; putative protoporphyrinogen oxidase K02493; Psort location: Cytoplasmic, score: 9.97.
       0.589
KXU58605.1
Sua5/YciO/YrdC/YwlC family protein; KEGG: ova:OBV_22440 1.3e-27 coaE; dephospho-CoA kinase K07566; Psort location: Cytoplasmic, score: 8.96.
       0.589
KXU59305.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
  
     0.546
tdk
Thymidine kinase; KEGG: stj:SALIVA_1264 4.6e-92 tdk; thymidine kinase; Psort location: Cytoplasmic, score: 9.97.
       0.522
EzrA
Septation ring formation regulator EzrA; KEGG: tva:TVAG_387410 4.5e-09 viral A-type inclusion protein; K02331 DNA polymerase phi subunit; Psort location: Cytoplasmic, score: 8.96.
  
     0.430
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.