| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXU57005.1 | KXU57900.1 | HMPREF3219_0201551 | HMPREF3219_0201051 | KEGG: stf:Ssal_01222 4.2e-130 glutamine transport ATP-binding protein GlnQ; K10041 putative glutamine transport system ATP-binding protein; Psort location: CytoplasmicMembrane, score: 10.00. | ABC transporter, ATP-binding protein; KEGG: sgg:SGGBAA2069_c12910 1.7e-236 putative ABC transporter ATP-binding protein K06147; Psort location: CytoplasmicMembrane, score: 10.00. | 0.563 |
| KXU57005.1 | KXU58609.1 | HMPREF3219_0201551 | HMPREF3219_0200651 | KEGG: stf:Ssal_01222 4.2e-130 glutamine transport ATP-binding protein GlnQ; K10041 putative glutamine transport system ATP-binding protein; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: sgg:SGGBAA2069_c10180 1.4e-193 ABC transporter membrane protein K06148; Psort location: CytoplasmicMembrane, score: 10.00. | 0.444 |
| KXU57005.1 | KXU58610.1 | HMPREF3219_0201551 | HMPREF3219_0200652 | KEGG: stf:Ssal_01222 4.2e-130 glutamine transport ATP-binding protein GlnQ; K10041 putative glutamine transport system ATP-binding protein; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: sgg:SGGBAA2069_c10190 4.9e-207 ABC transporter ATP-binding protein/permease K06147; Psort location: CytoplasmicMembrane, score: 10.00. | 0.549 |
| KXU57005.1 | KXU59293.1 | HMPREF3219_0201551 | HMPREF3219_0200261 | KEGG: stf:Ssal_01222 4.2e-130 glutamine transport ATP-binding protein GlnQ; K10041 putative glutamine transport system ATP-binding protein; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: sgg:SGGBAA2069_c12790 3.9e-262 ATP-binding protein K06147; Psort location: CytoplasmicMembrane, score: 10.00. | 0.482 |
| KXU57545.1 | KXU57900.1 | HMPREF3219_0201352 | HMPREF3219_0201051 | Putative bacteriocin export ABC transporter; KEGG: stj:SALIVA_1352 9.6e-124 lipoprotein-releasing system ATP-binding protein lolD; Psort location: CytoplasmicMembrane, score: 9.82. | ABC transporter, ATP-binding protein; KEGG: sgg:SGGBAA2069_c12910 1.7e-236 putative ABC transporter ATP-binding protein K06147; Psort location: CytoplasmicMembrane, score: 10.00. | 0.737 |
| KXU57545.1 | KXU58609.1 | HMPREF3219_0201352 | HMPREF3219_0200651 | Putative bacteriocin export ABC transporter; KEGG: stj:SALIVA_1352 9.6e-124 lipoprotein-releasing system ATP-binding protein lolD; Psort location: CytoplasmicMembrane, score: 9.82. | KEGG: sgg:SGGBAA2069_c10180 1.4e-193 ABC transporter membrane protein K06148; Psort location: CytoplasmicMembrane, score: 10.00. | 0.555 |
| KXU57545.1 | KXU58610.1 | HMPREF3219_0201352 | HMPREF3219_0200652 | Putative bacteriocin export ABC transporter; KEGG: stj:SALIVA_1352 9.6e-124 lipoprotein-releasing system ATP-binding protein lolD; Psort location: CytoplasmicMembrane, score: 9.82. | KEGG: sgg:SGGBAA2069_c10190 4.9e-207 ABC transporter ATP-binding protein/permease K06147; Psort location: CytoplasmicMembrane, score: 10.00. | 0.618 |
| KXU57545.1 | KXU59293.1 | HMPREF3219_0201352 | HMPREF3219_0200261 | Putative bacteriocin export ABC transporter; KEGG: stj:SALIVA_1352 9.6e-124 lipoprotein-releasing system ATP-binding protein lolD; Psort location: CytoplasmicMembrane, score: 9.82. | KEGG: sgg:SGGBAA2069_c12790 3.9e-262 ATP-binding protein K06147; Psort location: CytoplasmicMembrane, score: 10.00. | 0.542 |
| KXU57900.1 | KXU57005.1 | HMPREF3219_0201051 | HMPREF3219_0201551 | ABC transporter, ATP-binding protein; KEGG: sgg:SGGBAA2069_c12910 1.7e-236 putative ABC transporter ATP-binding protein K06147; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: stf:Ssal_01222 4.2e-130 glutamine transport ATP-binding protein GlnQ; K10041 putative glutamine transport system ATP-binding protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.563 |
| KXU57900.1 | KXU57545.1 | HMPREF3219_0201051 | HMPREF3219_0201352 | ABC transporter, ATP-binding protein; KEGG: sgg:SGGBAA2069_c12910 1.7e-236 putative ABC transporter ATP-binding protein K06147; Psort location: CytoplasmicMembrane, score: 10.00. | Putative bacteriocin export ABC transporter; KEGG: stj:SALIVA_1352 9.6e-124 lipoprotein-releasing system ATP-binding protein lolD; Psort location: CytoplasmicMembrane, score: 9.82. | 0.737 |
| KXU57900.1 | KXU58610.1 | HMPREF3219_0201051 | HMPREF3219_0200652 | ABC transporter, ATP-binding protein; KEGG: sgg:SGGBAA2069_c12910 1.7e-236 putative ABC transporter ATP-binding protein K06147; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: sgg:SGGBAA2069_c10190 4.9e-207 ABC transporter ATP-binding protein/permease K06147; Psort location: CytoplasmicMembrane, score: 10.00. | 0.535 |
| KXU58607.1 | KXU58608.1 | HMPREF3219_0200649 | HMPREF3219_0200650 | Hypothetical protein; KEGG: stz:SPYALAB49_000865 2.0e-130 phosphoenolpyruvate carboxylase; Psort location: Cytoplasmic, score: 8.96. | Pneumococcal vaccine antigen A-like family protein. | 0.829 |
| KXU58607.1 | KXU58609.1 | HMPREF3219_0200649 | HMPREF3219_0200651 | Hypothetical protein; KEGG: stz:SPYALAB49_000865 2.0e-130 phosphoenolpyruvate carboxylase; Psort location: Cytoplasmic, score: 8.96. | KEGG: sgg:SGGBAA2069_c10180 1.4e-193 ABC transporter membrane protein K06148; Psort location: CytoplasmicMembrane, score: 10.00. | 0.708 |
| KXU58607.1 | KXU58610.1 | HMPREF3219_0200649 | HMPREF3219_0200652 | Hypothetical protein; KEGG: stz:SPYALAB49_000865 2.0e-130 phosphoenolpyruvate carboxylase; Psort location: Cytoplasmic, score: 8.96. | KEGG: sgg:SGGBAA2069_c10190 4.9e-207 ABC transporter ATP-binding protein/permease K06147; Psort location: CytoplasmicMembrane, score: 10.00. | 0.708 |
| KXU58607.1 | glyA | HMPREF3219_0200649 | HMPREF3219_0200648 | Hypothetical protein; KEGG: stz:SPYALAB49_000865 2.0e-130 phosphoenolpyruvate carboxylase; Psort location: Cytoplasmic, score: 8.96. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.800 |
| KXU58608.1 | KXU58607.1 | HMPREF3219_0200650 | HMPREF3219_0200649 | Pneumococcal vaccine antigen A-like family protein. | Hypothetical protein; KEGG: stz:SPYALAB49_000865 2.0e-130 phosphoenolpyruvate carboxylase; Psort location: Cytoplasmic, score: 8.96. | 0.829 |
| KXU58608.1 | KXU58609.1 | HMPREF3219_0200650 | HMPREF3219_0200651 | Pneumococcal vaccine antigen A-like family protein. | KEGG: sgg:SGGBAA2069_c10180 1.4e-193 ABC transporter membrane protein K06148; Psort location: CytoplasmicMembrane, score: 10.00. | 0.708 |
| KXU58608.1 | KXU58610.1 | HMPREF3219_0200650 | HMPREF3219_0200652 | Pneumococcal vaccine antigen A-like family protein. | KEGG: sgg:SGGBAA2069_c10190 4.9e-207 ABC transporter ATP-binding protein/permease K06147; Psort location: CytoplasmicMembrane, score: 10.00. | 0.708 |
| KXU58608.1 | dltC | HMPREF3219_0200650 | HMPREF3219_0200656 | Pneumococcal vaccine antigen A-like family protein. | D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.410 |
| KXU58608.1 | glyA | HMPREF3219_0200650 | HMPREF3219_0200648 | Pneumococcal vaccine antigen A-like family protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.801 |