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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU58446.1preQ(1) synthase; KEGG: ssr:SALIVB_0884 1.1e-88 queF; NADPH-dependent 7-cyano-7-deazaguanine reductase K09457; Psort location: Cytoplasmic, score: 9.97. (187 aa)    
Predicted Functional Partners:
KXU58442.1
Protein ExsB; KEGG: ssr:SALIVB_0881 3.8e-113 queC; queuosine biosynthesis protein queC K06920; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.997
KXU58443.1
Queuosine biosynthesis protein QueD; KEGG: ssr:SALIVB_0882 3.8e-74 ygcM; putative 6-pyruvoyl tetrahydrobiopterin synthase (PTPS) (PTP synthase) K01737; Psort location: Cytoplasmic, score: 9.26.
 
  
 0.953
KXU58445.1
Putative 7-cyano-7-deazaguanosine biosynthesis protein QueE; KEGG: ppo:PPM_1044 4.6e-37 queE3; ribosomal RNA large subunit methyltransferase N K10026.
 
  
 0.940
KXU58444.1
Hypothetical protein; KEGG: ppo:PPM_1044 5.3e-20 queE3; ribosomal RNA large subunit methyltransferase N K10026.
  
  
 0.928
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
    
 0.688
nrdG
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
  
  
 0.585
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.567
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.531
KXU59009.1
Cadmium resistance transporter family protein; Psort location: CytoplasmicMembrane, score: 10.00.
   
    0.485
KXU58441.1
KEGG: fta:FTA_1583 7.9e-26 endoribonuclease L-PSP K07567; Psort location: Cytoplasmic, score: 9.97.
       0.464
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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