STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU58449.1Hypothetical protein; KEGG: mem:Memar_2145 1.9e-06 LPPG:FO 2-phospho-L-lactate transferase; K11212 LPPG:FO 2-phospho-L-lactate transferase; Psort location: Cytoplasmic, score: 8.96. (324 aa)    
Predicted Functional Partners:
KXU58448.1
Hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.946
KXU58450.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.938
KXU58447.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.800
KXU58451.1
Putative dipeptidase B; KEGG: stf:Ssal_00974 5.9e-250 pepDA; dipeptidase A; K08659 dipeptidase.
       0.756
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.627
PppL
Putative serine/threonine phosphatase stp; KEGG: stj:SALIVA_1501 3.9e-127 prpC; protein phosphatase prpC; Psort location: Cytoplasmic, score: 8.96.
   
  
 0.544
KXU59505.1
Biofilm regulatory protein A; KEGG: ddi:DDB_G0293168 0.0035 ddx17; DEAD/DEAH box helicase; K12823 ATP-dependent RNA helicase DDX5/DBP2; Psort location: CytoplasmicMembrane, score: 9.97.
  
     0.538
KXU57878.1
KEGG: ssr:SALIVB_1527 7.8e-232 glmU; bifunctional glmU UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase K04042; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.514
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.