STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU58478.1ROK family protein; KEGG: stj:SALIVA_1184 6.4e-150 sugar kinase; Psort location: Cytoplasmic, score: 9.26. (306 aa)    
Predicted Functional Partners:
KXU59632.1
KEGG: ssr:SALIVB_0208 0. exp5; PTS system glucose-specific EIICBA component; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.999
ScrA2
KEGG: stf:Ssal_00287 0. scrA; PTS system sucrose-specific transporter subunit IIBC; K02808 PTS system, sucrose-specific IIA component; K02809 PTS system, sucrose-specific IIB component K02810; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.999
RbgA
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
       0.786
RnhB1
Ribonuclease HII; KEGG: stj:SALIVA_1185 7.1e-128 ribonuclease HII (RNase HII); Psort location: Cytoplasmic, score: 9.97.
       0.786
DprA
KEGG: apb:SAR116_0616 5.4e-43 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96.
  
    0.616
GdhA
KEGG: stj:SALIVA_0404 1.0e-236 gdhA; NADP-specific glutamate dehydrogenase (NADP-GDH).
      
 0.598
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.516
KXU59317.1
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: stj:SALIVA_0383 0. fruA; PTS system fructose-specific EIIABC component (EIIABC-Fru); Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.503
KXU58475.1
DNA-binding helix-turn-helix protein; KEGG: sgg:SGGBAA2069_c10720 1.6e-91 transcriptional regulator; Psort location: Cytoplasmic, score: 8.96.
       0.484
LacS
Glycoside/pentoside/hexuronide transporter; KEGG: stj:SALIVA_1400 0. lacS; lactose permease; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.437
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.