STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU58331.1Hypothetical protein; KEGG: gpo:GPOL_c18530 8.4e-05 putative pyrazinamidase/nicotinamidase; K08281 nicotinamidase/pyrazinamidase. (155 aa)    
Predicted Functional Partners:
Dut
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
     
 0.786
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.573
gpsA
KEGG: stf:Ssal_00176 5.7e-181 gpsA; glycerol-3-phosphate dehydrogenase [NAD(P)+]; K00057 glycerol-3-phosphate dehydrogenase (NAD(P)+); Psort location: Cytoplasmic, score: 9.97; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
   0.552
BirA
biotin--[acetyl-CoA-carboxylase] ligase; KEGG: stj:SALIVA_0965 1.5e-159 birA; bifunctional biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase; Psort location: Cytoplasmic, score: 9.26.
     
 0.531
KXU58275.1
KEGG: stj:SALIVA_1949 0. adhE; aldehyde-alcohol dehydrogenase 2; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.495
KXU58329.1
Flavin reductase; KEGG: ssr:SALIVB_1965 1.2e-98 oxidoreductase; Psort location: Cytoplasmic, score: 9.97.
     
 0.489
KXU59298.1
KEGG: stj:SALIVA_0403 2.3e-186 nadR; putative nicotinamide-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 8.96.
     
 0.471
KXU58328.1
Flavin reductase; KEGG: ssr:SALIVB_1966 1.1e-223 oxidoreductase; Psort location: Cytoplasmic, score: 9.97.
       0.462
KXU58333.1
Hypothetical protein.
       0.418
KXU57825.1
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.2e-13 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96.
     
 0.405
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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