STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU58080.1KEGG: stl:stu1642 4.8e-129 ABC transporter ATP binding protein; K02013 iron complex transport system ATP-binding protein; Psort location: CytoplasmicMembrane, score: 7.88. (260 aa)    
Predicted Functional Partners:
KXU58498.1
ABC transporter, substrate-binding protein, QAT family; KEGG: stj:SALIVA_1161 1.2e-228 glycine betaine/L-proline ABC transporter,permease/glycine betaine/L-proline-binding protein; Psort location: CytoplasmicMembrane, score: 10.00.
    
  0.825
PotA1
ABC transporter, ATP-binding protein; KEGG: ssr:SALIVB_1052 2.5e-196 ugpC; sn-glycerol-3-phosphate import ATP-binding protein ugpC K10112; Psort location: CytoplasmicMembrane, score: 7.88.
    
 
0.764
potA
Putative spermidine/putrescine ABC transporter, ATP-binding protein PotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
  
  
 
0.669
HlyX
Hypothetical protein; KEGG: apb:SAR116_1911 7.6e-44 hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.609
AdcC1
ABC transporter, ATP-binding protein; KEGG: ssr:SALIVB_0205 7.5e-124 adcC; zinc (Zn2+) ABC uptake transporter ATP-binding protein; K09817 zinc transport system ATP-binding protein.
  
  
 
0.526
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
 
    0.498
CbiO1
KEGG: stj:SALIVA_0280 2.1e-119 cbiO; cobalt import ATP-binding protein cbiO; Psort location: CytoplasmicMembrane, score: 7.88.
  
 
  0.453
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
   0.432
KXU56422.1
KEGG: ssr:SALIVB_2136 1.4e-76 cbiO1; cobalt import ATP-binding protein cbiO 1 K02006; Psort location: CytoplasmicMembrane, score: 9.82.
  
 
  0.403
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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