STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (347 aa)    
Predicted Functional Partners:
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
 
 
 0.974
queG
KEGG: gym:GYMC10_0856 6.6e-77 iron-sulfur cluster-binding protein; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.747
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
  
 0.739
KXU56787.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
  
     0.735
RuvA
KEGG: stj:SALIVA_0068 2.1e-96 ruvA; holliday junction ATP-dependent DNA helicase ruvA; Psort location: Cytoplasmic, score: 9.26.
  
    0.617
KXU57895.1
Glucosamine-6-phosphate deaminase; KEGG: ssr:SALIVB_1549 5.5e-112 hypothetical protein; K02564 glucosamine-6-phosphate deaminase; Psort location: Cytoplasmic, score: 8.96.
       0.609
KXU58244.1
Oligopeptide-binding protein AmiA; KEGG: mct:MCR_1303 9.7e-163 oppA; oligopeptide ABC transport system substrate binding protein OppA K15580; Psort location: Periplasmic, score: 9.94.
      
 0.583
KXU56169.1
Oligopeptide-binding protein AmiA; KEGG: mct:MCR_1303 3.4e-167 oppA; oligopeptide ABC transport system substrate binding protein OppA K15580; Psort location: Periplasmic, score: 9.99.
      
 0.583
KXU57896.1
Hypothetical protein.
       0.568
RecJ
KEGG: stf:Ssal_01299 0. recJ; single-stranded-DNA-specific exonuclease RecJ; K07462 single-stranded-DNA-specific exonuclease; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.548
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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