| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PurL | PyrB | HMPREF3219_0201436 | HMPREF3219_0201063 | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | KEGG: stf:Ssal_01641 2.1e-160 pyrB; aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97. | 0.650 |
| PurL | PyrF | HMPREF3219_0201436 | HMPREF3219_0200781 | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | KEGG: stj:SALIVA_1119 7.4e-117 pyrF; orotidine 5-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase); Psort location: Cytoplasmic, score: 9.97. | 0.637 |
| PurL | argG | HMPREF3219_0201436 | HMPREF3219_0200891 | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | KEGG: stw:Y1U_C1702 3.7e-209 argininosuccinate synthase; K01940 argininosuccinate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.487 |
| PurL | carA | HMPREF3219_0201436 | HMPREF3219_0201062 | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | KEGG: stj:SALIVA_0507 2.1e-192 carA; carbamoyl-phosphate synthase small chain; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. | 0.955 |
| PurL | carB | HMPREF3219_0201436 | HMPREF3219_0201061 | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | KEGG: stj:SALIVA_0508 0. carB; carbamoyl-phosphate synthase large chain; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | 0.693 |
| PurL | glmS | HMPREF3219_0201436 | HMPREF3219_0200705 | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.575 |
| PurL | glnA | HMPREF3219_0201436 | HMPREF3219_0200513 | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | KEGG: ssr:SALIVB_1911 7.9e-239 glnA; glutamine synthetase K01915; Psort location: Cytoplasmic, score: 9.97. | 0.406 |
| PurL | purF | HMPREF3219_0201436 | HMPREF3219_0201455 | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.973 |
| PurL | pyrC | HMPREF3219_0201436 | HMPREF3219_0201918 | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.602 |
| PurL | pyrE | HMPREF3219_0201436 | HMPREF3219_0200782 | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.666 |
| PyrB | PurL | HMPREF3219_0201063 | HMPREF3219_0201436 | KEGG: stf:Ssal_01641 2.1e-160 pyrB; aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97. | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | 0.650 |
| PyrB | PyrF | HMPREF3219_0201063 | HMPREF3219_0200781 | KEGG: stf:Ssal_01641 2.1e-160 pyrB; aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97. | KEGG: stj:SALIVA_1119 7.4e-117 pyrF; orotidine 5-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase); Psort location: Cytoplasmic, score: 9.97. | 0.934 |
| PyrB | argG | HMPREF3219_0201063 | HMPREF3219_0200891 | KEGG: stf:Ssal_01641 2.1e-160 pyrB; aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97. | KEGG: stw:Y1U_C1702 3.7e-209 argininosuccinate synthase; K01940 argininosuccinate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.903 |
| PyrB | carA | HMPREF3219_0201063 | HMPREF3219_0201062 | KEGG: stf:Ssal_01641 2.1e-160 pyrB; aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97. | KEGG: stj:SALIVA_0507 2.1e-192 carA; carbamoyl-phosphate synthase small chain; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. | 0.999 |
| PyrB | carB | HMPREF3219_0201063 | HMPREF3219_0201061 | KEGG: stf:Ssal_01641 2.1e-160 pyrB; aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97. | KEGG: stj:SALIVA_0508 0. carB; carbamoyl-phosphate synthase large chain; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | 0.999 |
| PyrB | purF | HMPREF3219_0201063 | HMPREF3219_0201455 | KEGG: stf:Ssal_01641 2.1e-160 pyrB; aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.417 |
| PyrB | pyrC | HMPREF3219_0201063 | HMPREF3219_0201918 | KEGG: stf:Ssal_01641 2.1e-160 pyrB; aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
| PyrB | pyrE | HMPREF3219_0201063 | HMPREF3219_0200782 | KEGG: stf:Ssal_01641 2.1e-160 pyrB; aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.935 |
| PyrF | PurL | HMPREF3219_0200781 | HMPREF3219_0201436 | KEGG: stj:SALIVA_1119 7.4e-117 pyrF; orotidine 5-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase); Psort location: Cytoplasmic, score: 9.97. | KEGG: stj:SALIVA_0041 0. purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase); Psort location: Cytoplasmic, score: 9.97. | 0.637 |
| PyrF | PyrB | HMPREF3219_0200781 | HMPREF3219_0201063 | KEGG: stj:SALIVA_1119 7.4e-117 pyrF; orotidine 5-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase); Psort location: Cytoplasmic, score: 9.97. | KEGG: stf:Ssal_01641 2.1e-160 pyrB; aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97. | 0.934 |